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KMID : 0385219940040020112
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Korean Journal of Gerontology
1994 Volume.4 No. 2 p.112 ~ p.120
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Blood and Plasma Vitamin C Concentration and Plasma Protein Carbonyl Formation in Koreans
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Choi Young-Beom
Shin Sun-Kyoung
Lee Gwang-Ho
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Abstract
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Recommended dietary allowance (RDA) of vitamin C was determined on the bases of preventing symptoms and signs of the scurvy, and reaching the threshold for urinary excretion without consideration of the important function of the vitamin C as a first line antioxidant and without idea of the infection or disease status of koreans. This RDA may be below the optimal amount for the optimal functions of the vitamin C dependent metabolism of the human body, So we measured the whole blood and plasma vitamin C concentrations, and plasma protein carbonyl content of the heathy adult korean people belong to mid to high socioeconomic status from 1992 to 1993. Whole blood and plasma vitamin C concentrations were l.62±0.50 ㎎/dl and 1.20±0.42 ㎎/dl respectively. There existed an close relationship between whole blood and plasma vitamin C concentrations (r=0.82, p=0). There were not significant changes of whole blood and plasma vitamin C concentrations as the age became older. But whole blood and plasma vitamin C concentrations were significantly lower in males than in females of the each age group. Plasma protein carbonyl contents were 0.99±0.15 nmol/㎎ of protein, The hypothesis that plasma protein carbonyl content would be lower if high whole blood or plasma vitamin C concentrations, and vice versa was not confirmed in this study. There were no relationships among plasma protein carbonyl contents, age and vitamin C concentrations. So we could not confirm the adequacy of the whole blood and plasma vitamin C concentrations of koreans by the plasma protein carbonyl content.
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KEYWORD
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whole blood, plasma, vitamin C, carbonyl
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